香港六合彩

姓名：李慧臻

工作单位：香港六合彩-香港六合彩开奖

职称：讲师

通信地址：浙江省宁波市北仑区梅山街道七星南路169号

联系方式：[email protected]；[email protected]

个人简介：

李慧臻，工学博士，主要从事益生菌种质资源开发、益生菌功能机制解析、膳食功能因子挖掘与利用、肠道微生物与宿主健康和功能食品研究与开发等方面的研究。在国内外高水平期刊上发表论文20余篇，其中以第一作者在Journal of Agricultural and Food Chemistry、Food Science and Human Wellness、International Journal of Biological Macromolecules和Food Bioscience等期刊上发表论文9篇，获得授权发明专利1项。担任Food Research International、International Journal of Biological Macromolecules、Food Bioscience、Journal of Functional Foods和Journal of Agriculture and Food Research等期刊的审稿人。

教育及工作经历：

2012.09-2016.06 安阳工香港六合彩开奖网 食品科学与工程 学士

2017.09-2020.06 东北农业大学 食品科学 硕士 导师：霍贵成教授

2020.09-2025.06 江南大学 食品科学与工程 博士 导师：李海涛教授、杨波研究员（陈卫院士团队）

2025.08-至今 香港六合彩开奖网 食品科学与工程香港六合彩开奖网 讲师

参与项目：

1. 国家重点研发计划项目子课题，益生菌微生态健康调节机制与新型营养健康食品研发

2. 国家自然科学基金，短双歧杆菌CCFM683对肠道屏障的保护机制

3. 企业横向，益生菌改善幼年大鼠消化能力的研究

4. 企业横向，益生菌与后生元的功效评价（基于动物实验）

代表性论文：

1. Huizhen Li, Yan Jin*, Haitao Li, Jianxin Zhao, Catherine Stanton, R. Paul Ross, Wei Chen, Bo Yang*. Understanding exopolysaccharides from lactic acid bacteria: synthesis, functions, and applications[J]. Journal of Agricultural and Food Chemistry, 2025.

2. Huizhen Li, Yang Chen, Huiting Fang, Xinmei Guo, Xuecong Liu, Jianxin Zhao, Wei Chen, Bo Yang*. Lactobacillus rhamnosus MP108 alleviates ulcerative colitis in mice by enhancing the intestinal barrier, inhibiting inflammation, and modulating gut microbiota[J]. Food Science and Human Wellness, 2025, 14(6): 9250139.

3. Huizhen Li, Xinmei Guo, Xuecong Liu, Jianxin Zhao, Wei Chen, Bo Yang*. Protective effect of a cocktail of lactic acid bacteria on DSS-induced ulcerative colitis via activating the TGR5/PKA pathway[J]. Food Bioscience, 2024, 62: 105326.

4. Huizhen Li, Haitao Li*, Catherine Stanton, R. Paul Ross, Jianxin Zhao, Wei Chen, Bo Yang*. Exopolysaccharides produced by Bifidobacterium longum subsp. longum YS108R ameliorates DSS-induced ulcerative colitis in mice by improving the gut barrier and regulating the gut microbiota[J]. Journal of Agricultural and Food Chemistry, 2024, 72(13): 7055-7073.

5. Huizhen Li, Haitao Li*, Catherine Stanton, R. Paul Ross, Jianxin Zhao, Wei Chen, Bo Yang*. Alleviative effects of exopolysaccharides from Limosilactobacillus mucosae CCFM1273 against ulcerative colitis via modulation of gut microbiota and inhibition of Fas/Fasl and TLR4/NF-κB pathways[J]. International Journal of Biological Macromolecules, 2024, 260: 129346.

6. Huizhen Li, Jialu Shi, Li Zhao, Jiaqi Guan, Fei Liu, Guicheng Huo, Bailiang Li*. Lactobacillus plantarum KLDS1.0344 and Lactobacillus acidophilus KLDS1.0901 mixture prevents chronic alcoholic liver injury in mice by protecting the intestinal barrier and regulating gut microbiota and liver-related pathways[J]. Journal of Agricultural and Food Chemistry, 2020, 69(1): 183-197.（高被引）

7. Huizhen Li, Fei Liu, Jingjing Lu, Jialu Shi, Jiaqi Guan, Fenfen Yan, Bailiang Li*, Guicheng Huo*. Probiotic mixture of Lactobacillus plantarum strains improves lipid metabolism and gut microbiota structure in high fat diet-fed mice[J]. Frontiers in Microbiology, 2020, 11: 512.

授权发明专利：

李柏良, 李慧臻, 柯楚新, 刘飞, 王松, 霍贵成. 一种预防急、慢性酒精性肝损伤的乳酸菌配方及其应用. 授权号: CN111437294B.